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cryo-EM Facility - Associate/Full Specialist

Application Window

Open date: October 17, 2023

Most recent review date: Thursday, Feb 29, 2024 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Thursday, Apr 17, 2025 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

cryo-EM Facility – Associate/Full Specialist
Department of Biochemistry and Biophysics
UC San Francisco

We seek to hire a cryo-EM Tomography expert, at the level of Associate Specialist or Specialist. The cryo-EM facility at UCSF is directed by David Agard, Yifan Cheng and Klim Verba. Our facility currently houses a ThermoFisher FEI Titan Krios with a post-GIF K3, a Talos Arctica with a K3 camera, and a special narrow polepiece Glacios equipped with a K3. For FIB milling, we have an Aquilos 2 cryo-FIB-SEM with iFLIM. The facility is supervised by a manager who oversees microscope maintenance and an IT specialist who oversees data management. The facility has over 100 regular users and is continually training new users.

The Associate Specialist or Specialist will focus on cryo-EM Tomography and FIB-SEM, providing support and training for the growing UCSF cryo-ET community. In additional, they will help with the collection of high-quality cryo-ET data. They will facilitate users carrying out sample preparation and data acquisition for cryo-ET. In addition, they will participate in various Cryo-ET collaborative projects, particularly from nonstructural biology laboratories.

Required Qualifications:

  • Specialists appointed at the Associate rank must possess a master’s degree (or equivalent degree) in a biological or materials science (or related field) or five to ten years of research experience.
  • Specialists appointed at the Full rank must possess a terminal degree (or equivalent degree) in a biological or materials science (or related field) or ten or more years of research experience.
  • 5+ years of previous experience in all aspects of cryo-EM, including operating high-end instruments, such as Titan Krios, Arctica and Galacios.
  • At least 1 year experience in cryo-ET data collection and processing and FIB-SEM operation.

Preferred Qualifications:

  • Experience in all perspective of cryo-EM, both single particle and cryo-ET.
  • Good biochemistry and/or cell biology skills.

Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $70,500-$181,800.

Please apply online at: with a cover letter, CV, and contact information for two references. Applicant materials must list current and/or pending qualifications upon submission. The selected candidate must meet all the qualifications at the time of appointment.

Application Requirements

Document requirements
  • Cover Letter

  • Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).

  • Statement of Research (Optional)

  • Statement of Teaching (Optional)

  • Statement of Contributions to Diversity - Please see the following page for more details: Contributions to Diversity Statement

  • Misc / Additional (Optional)

Reference requirements
  • 2 required (contact information only)

About UC San Francisco

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

Job location

San Francisco, CA