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Specialist – Stem Cell Biology & Proteomics

Application Window

Open date: July 18, 2022

Most recent review date: Friday, Sep 9, 2022 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Thursday, Jan 18, 2024 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

Specialist – Stem Cell Biology & Proteomics

The Krogan Lab (http://kroganlab.ucsf.edu) is a highly dynamic and collaborative laboratory focusing on the molecular networks underpinning neurological disorders, infectious disease, and carcinogenesis. You will be focusing on culturing iPSCs and iPSC-derived cell types (e.g. neurons, cardiomyocytes) and mapping protein-protein interactions (PPI) and signaling networks in healthy state and disease using mass spectrometry. This role is an excellent opportunity to learn a number of valuable, cutting-edge techniques in proteomics while working with a dynamic and interdisciplinary research team. The candidate will characterize new iPSC lines expressing affinity-tagged proteins of interest for PPI mapping, prepare samples for proteomic analysis and perform functional validation studies involving CRISPR-based technologies and imaging. The candidate will also have the opportunity to develop and implement new protocols for mass spectrometry-based proteomics experiments in neurons and other cell types.

Our ideal applicant is a problem solver with a positive attitude, excellent organizational and interpersonal skills, and the ability to learn and implement methodology efficiently. Candidate’s CV and/or cover letter must state basic qualifications (or if pending) upon submission. Candidates must meet all qualifications by the time of hire.

Required Qualifications:
● Jr. Specialist rank: Bachelor’s degree in biological sciences or an appropriate scientific field.
● Assistant rank: Master’s degree, or Bachelor’s degree and 5-10 years of work experience in biological sciences or an appropriate scientific field.
● Associate rank: Master’s degree, or Bachelor’s degree and 5-10 years of work experience in biological sciences or an appropriate scientific field, in addition to a record of academic accomplishments, including contributions to published or in-press research in the field and a demonstrated record of University and/or public service.
● Experience in Molecular biology techniques including molecular cloning, PCR, and western blotting.
● Cell/tissue culture experience.
● Able to work independently and meet deadlines; recognize and resolve problems while maintaining a high level of organization.
● Effective verbal and written communication skills to interface with the team to review and analyze the results.
● Experience in Microsoft Office (Word, Excel, and/or Powerpoint).

Preferred Qualifications:
● Experience culturing iPSCs and iPSC-derived cells.
● Experience with neuronal or cardiomyocyte cultures.
● Generating new cell lines and characterizing them.
● with CRISPR/gene editing techniques
● DNA/RNA Blotting.
● Transfection or viral transduction.
● Affinity purifications of proteins.
● Preparation for samples for mass spectrometric analysis.
● Fluorescence microscopy.
● Experience with mass spectrometry data.
● Experience with managing large datasets and/or databases.
● Experience with statistical data analysis

Please apply online at https://aprecruit.ucsf.edu/JPF04054, with a CV, cover letter, and two reference contacts.

Application Requirements

Document requirements
  • Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).

  • Cover Letter

Reference requirements
  • 2 required (contact information only)

Campus Information

As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy found here: https://policy.ucop.edu/doc/5000695/SARS-CoV-2_Covid-19.

UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

Job location

San Francisco, CA