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Biostatistician

Application Window

Open date: July 5, 2022

Most recent review date: Friday, Aug 5, 2022 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Friday, Jan 5, 2024 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

Proctor DCC Specialist Statistician

The Francis I. Proctor Foundation at the University of California, San Francisco is seeking a Biostatistician in the Academic Specialist job series (staff with full benefits) to help lead statistical research efforts in its Data Coordinating Center (DCC). The Proctor Foundation’s mission is to prevent blindness worldwide through research and teaching (https://proctor.ucsf.edu/), and it is one of the world’s leading clinical trial centers for eye-related intervention studies. Proctor faculty currently lead more than 20 randomized controlled trials throughout the world, funded by the National Institutes of Health and the Bill & Melinda Gates Foundation. Trials range in scale from hundreds- to hundreds of thousands of participants, and key areas of research include: interventions to support trachoma elimination, community-based screening to identify chronic eye disease, therapies to control uveitis, corneal surgery trials, and mass drug administration to reduce all-cause child mortality. Many trials use innovative designs, such as response-adaptive allocation and group-sequential testing. In addition to randomized controlled trials, many faculty lead large-scale observational studies using electronic health records data that include millions of people.

The Biostatistician will play a lead role in the DCC in the design and analysis of clinical trials, working in close collaboration with Proctor faculty and analysts. The Biostatistician will join an exceptional team at Proctor, with latitude to lead methodologic research in clinical trial design and analysis topics, drawing on Proctor’s extensive past and ongoing trials. The position is ideally suited for people with PhD-level training in biostatistics or statistics, but we will consider exceptional candidates with a combination of a master’s degree and relevant experience working on clinical trials or field trials.

Key responsibilities in the DCC will include:

  • Work with faculty on study design (e.g., sample size, sampling approaches)
  • Develop statistical analysis plans for trials
  • Lead interim and primary endpoint analyses for trials
  • Work with faculty and data and safety monitoring committees to monitor trials, including closed (masked) interim efficacy and futility analyses
  • Work with- and mentor/advise analysts to develop:
    • reproducible, computational workflows
    • automated study monitoring reports
    • database and electronic data collection design
    • secondary outcome analyses for trials

Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.

Required Qualifications:

  • Specialists appointed at the Assistant or Associate rank must possess (or in process of obtaining) a Master’s degree in biostatistics, statistics, or related discipline plus at least 4 year’s experience working as a statistician on prospective clinical trials.
  • Specialists appointed at the full rank must possess (or in process of obtaining) a PhD in biostatistics, statistics or a related discipline plus at least 2 year’s experience working on prospective clinical trials.
  • Applicants must have obtained the degree requirement for the Specialist rank by the time of hire.
  • Familiarity with epidemiologic trial design and conduct.
  • Strong analytic skills: should be adept at programming and data analysis (preferably R).
  • Experience leading small teams (<10) of masters-level statisticians or data scientists.
  • Good communication (writing and speaking).
  • Publication records commensurate with experience, with an emphasis on collaborative contributions.
  • Applicant’s materials must list (pending) qualifications upon submission.

Preferred Qualifications:

  • 4 or more years of experience working as a statistician on prospective clinical trials.
  • Experience with causal inference methods (e.g., DAGs, structural causal models), and transparent/ reproducible data science tools (e.g., GitHub, R markdown).
  • Experience and/or interest in international research.
  • Experience and/or interest in adaptive designs.
  • Interest in clinical trial methodology.

Please apply online at https://aprecruit.ucsf.edu/JPF04037.

Application Requirements

Document requirements
  • Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).

  • Cover Letter

  • Statement of Research (Optional)

  • Statement of Teaching (Optional)

  • Statement of Contributions to Diversity - Please see the following page for more details: https://diversity.ucsf.edu/contributions-to-diversity-statement
    (Optional)

Reference requirements
  • 3 required (contact information only)

Campus Information

As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy found here: https://policy.ucop.edu/doc/5000695/SARS-CoV-2_Covid-19.

UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

Job location

San Francisco, CA