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Junior Specialist – Schumacher Lab

Application Window

Open date: September 8, 2021

Most recent review date: Thursday, Sep 23, 2021 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Wednesday, Mar 8, 2023 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

Junior Specialist – Schumacher Lab
University of California, San Francisco
Department of Anesthesia & Perioperative Care

The Department of Anesthesia & Perioperative Care is seeking for a Junior Specialist. This Junior Specialist position is an integral part of the research team and will assist and collaborate with the principal investigators in the study of the neurobiology of peripheral pain transduction. Focus areas include chemotherapy induced peripheral neuropathy and understanding the analgesic action of minor cannabinoids. Responsibilities include overall laboratory management, oversight of transgenic mouse colony / husbandry, supervision of undergraduate rotation students, helping design then performing advanced molecular and cellular research techniques:

• Analyze nucleic acid sequence using tools in NCBI for optimal DNA primer design.
• Isolation and preparation of RNA and total protein from micro-dissected mouse spinal ganglion for deep sequencing.
• Isolation of nuclear chromatin and perform antibody – based pull-down assays such as ChIP for both quantitative ChIP and ChIP - Seq analysis.
• Perform quantitative RT PCR (qPCR) and Immuno-blot (Western blot) from mouse tissues, especially from sensory ganglion and analyze and plot data, perform basic statistical analysis using Graph Pad – Prism.
• Use of calcium imaging to quantitate primary sensory neuron responses to cold, heat, TRP channel activators.
• Primary culture of mouse dorsal root ganglion neurons.
• Maintenance and experimental use of established cell lines including HEK293, HEPG2, N2a.
• Mouse handling, intraperitoneal injections, use of inhaled anesthetic - for mouse mouse paw injections.
• Help design, perform and analyze nociceptive behavioral studies in mice including the cold plate and Hargreaves (thermal) paw withdrawal tests.
• Maintain and summarize laboratory data using Office Suite, Prizm computer programs.

Required Qualification:
• Specialists appointed at the junior rank must possess a baccalaureate degree with at least one or more years of research experience after completion of the baccalaureate degree.

Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public
Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period.

Please apply online at https://aprecruit.ucsf.edu/JPF03560.

UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

Application Requirements

Document requirements
  • Curriculum Vitae - Your most recently updated C.V.

  • Cover Letter (Optional)

  • Statement of Research (Optional)

  • Statement of Teaching (Optional)

  • Statement of Contributions to Diversity (Optional)

  • Misc / Additional (Optional)

Reference requirements
  • 2 required (contact information only)

Campus Information

As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy found here: https://policy.ucop.edu/doc/5000695/SARS-CoV-2_Covid-19.

UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

Job location

San Francisco, CA