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Junior Specialist – Aghi Lab

Recruitment Period

Open date: December 11th, 2018
Last review date: Wednesday, Jan 23, 2019 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.
Final date: Thursday, Jun 11, 2020 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.


Junior Specialist – Aghi Lab

The Department of Neurological Surgery is seeking a Junior Specialist. The person filling this position will participate in basic science research to study mechanisms of glioblastoma angiogenesis, mechanisms of resistance to currently used anti-angiogenic therapies, and what drug combinations are best suited to inhibit glioblastoma angiogenesis in mouse models of human glioblastomas. Job duties will include extraction of RNA and DNA form human glioblastoma tissue; immunohistochemistry and immunofluorescence of glioblastoma tissue and cultured primary glioblastoma cells; isolation of cells from glioblastoma tumors and flow cytometry of the cells to count numbers of various cell types; isolation of stem cells from human glioblastomas; CRISPR techniques; and intracranial and subcutaneous implantation of tumor cells into immunodeficient mice, followed by treatment and monitoring of these animals and euthanasia when appropriate. Also handles lab administration - order entry, making sure protocols are in compliance, and orienting new lab members. Other duties as assigned.

Required Qualifications:

  1. Specialists appointed at the junior rank must possess a baccalaureate degree (or equivalent degree) or at least four years of research experience (e.g., with instrumentation and research equipment, social science research methods, or creative activities).

  2. Experience with basic wet lab research (cell culture, pipetting, sectioning tissue, immunostaining, qPCR, mouse tumor implantation, western blotting).

  3. Ability to learn more advanced wet lab techniques (CRISPR, immunoprecipitation, purification of histidine-tagged proteins).

  4. Ability to independently plan experiments from start to finish to address a specific topic.

  5. Ability to write manuscripts that the PI would then edit before submission.

  6. Ability to handle lab administration, including order entry, making sure protocols are in compliance, and orienting new lab members.

Preferred Qualifications:

  1. Independent specialized research
  2. Management experience

Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training. Please apply online at

UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

Job location

San Francisco, CA


Document requirements
  • Curriculum Vitae - Your most recently updated C.V.

  • Cover Letter

  • Statement of Research

  • Statement of Teaching (Optional)

  • Statement of Contributions to Diversity (Optional)

  • Misc / Additional (Optional)

Reference requirements
  • 3 required (contact information only)